G23 Instruments was formed in 1996 at the Department of Pharmacology, University College London by Dave Osborne, the Senior Engineering Officer, to provide scientists with equipment and expertise. When Dave retired from UCL the running of the company was taken over by Dr Bob Muid.

The Pharmacology Department at UCL had long been associated with advanced research in the fields of electrophysiology, receptors, ion channels, neuropharmacology and immunopharmacology. It was the only Department in the UK to have been rated in the top category in all five UGC/HEFCE Research Assessment Exercises up to 2001, and was the top-ranked (5 star A) Department in the latter two exercises in 1996 and 2001. This grading is based on the research activities of all members of the staff and the expertise which had been developed to support the "leading edge" research workers is now available to other parties through G23 Instruments.

During the reorganisation of the Faculty of Life Sciences in 2008, the Deparment of Pharmacology was disestablished and its members became part of the new
Research Department of Neuroscience, Physiology & Pharmacology.

Dave Osborne still makes and designs our items and is actively involved in the company. When Bob Muid retired from UCL in 2010, G23 Instruments became an independent company.